The quantification of apoptotic cells by diagnostic kits is a widely used technique used to evaluate the cytotoxic effects of different compounds. Handling process induces, in many cells, the pass from normal to secondary necrosis stage affecting apoptotic cells determination and threfore, making unnaccurate quantifications. PRONACERA have developed a technology that stabilizes apoptotic cells, and thus a more reliable and accurate number of apoptotic cells can be determined.
Stabilization of apoptotic cells and delaying its entry into secondary necrosis is also important to avoid toxic and pro-inflammatory phenomena that induces cell death. Stabilization of apoptotic cells may be a protective mechanism to minimize the side effects of treatments that seek cell death.